Endocrine Abstracts

Hyponatraemia is a very common electrolyte abnormality with varied presenting features depending on the underlying cause. The authors report the case of a 75 years old, previously fit, gentleman who presented with weight loss, lethargy, and blackouts. He was admitted to the hospital repeatedly under the general physicians over an 8 month period.Investigations revealed persistent hyponatraemia (serum sodium 113–120 mmol/l, serum osmolality 258 mOsm/k...

Pituitary metastases are uncommon, with breast and lung carcinomas being the most common primary sites. Of the minority that are symptomatic, diabetes insipidus (DI) is frequently present. We report two cases, one presenting with DI and the other with hypopituitarism and DI, who deteriorated rapidly and died within 3 months.Case 1: A previously fit 53-year-old lady presented in December 2008 with a one month history of polyuria and polydipsia. Investigat...

Primary aldosteronism (PA) uncommonly presents during pregnancy. Uncontrolled blood pressure may result in adverse maternal and fetal outcomes. We report a case presenting in pregnancy whose management proved particularly challenging, due to variable compliance with therapy, frequent non-attendance at clinic, a subsequent pregnancy and negative imaging.A 24 year old woman presented at 26 weeks gestation with severe pre-eclampsi...

Primary aldosteronism (PA) uncommonly presents during pregnancy. Uncontrolled blood pressure may result in adverse maternal and fetal outcomes. We report a case presenting in pregnancy whose management proved particularly challenging, due to variable compliance with therapy, frequent non-attendance at clinic, a subsequent pregnancy and negative imaging.A 24 year old woman presented at 26 weeks gestation with severe pre-eclampsi...

Introduction: Craniopharyngiomas are usually benign intracranial tumours which can sometimes be locally aggressive. Malignant transformation is extremely rare and has a poor prognosis. We report a case of a patient who developed carcinomatous changes in a craniopharyngioma which was first excised almost 55 years ago.Case report: Mr AM was diagnosed with a craniopharyngioma at the age of 5 years. He underwent surgery in 1952 but was lost to follow up and ...